Of Mice and Men: NAD+ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients.
Of Mice and Men: NAD+ Boosting with Niacin Provides Hope for Mitochondrial Myopathy Patients.
Cell Metab. 2020 Jun 02;31(6):1041-1043
Authors: Chini EN
Abstract
In this issue of Cell Metabolism, Pirinen et al. (2020) show that disruption in NAD+ homeostasis is a key component of the pathogenesis of mitochondrial myopathy in humans that can be targeted by the administration of the NAD+ precursor niacin, identifying NAD+ boosting as a potential treatment for this devastating disease.
PMID: 32492387 [PubMed - as supplied by publisher]
Source: Cell Metabolism - Category: Cytology Authors: Chini EN Tags: Cell Metab Source Type: research