< p > Ansavaricin J, a New < a href="https://cn.bing.com/academic/profile?id=d9e2d477eec90ff106788fe4cb08f938 & amp;encoded=0 & amp;v=paper_preview & amp;mkt=zh-cn" target="_blank" > Heterocyclic & nbsp;Ring-fused & nbsp; < /a > Streptovaricin from Gene < em > stvP5 < /em > -deleted Mutant of < em > Streptomyces spectabilis < /em > CCTCC M2017417 < /p > .

<p>Ansavaricin J, a New <a href="https://cn.bing.com/academic/profile?id=d9e2d477eec90ff106788fe4cb08f938&amp;encoded=0&amp;v=paper_preview&amp;mkt=zh-cn" target="_blank">Heterocyclic&nbsp;Ring-fused&nbsp;</a>Streptovaricin from Gene <em>stvP5</em>-deleted Mutant of <em>Streptomyces spectabilis </em>CCTCC M2017417</p>. Chem Biodivers. 2020 Jun 03;: Authors: Liu Y, Chen X, Li ZY, Huang LX, Sun YH Abstract A new ring-fused streptovaricin analogue, named ansavaricin J ( 1 ), together with the known compound ansavaricin E, were unprecedently isolated from the culture of the genetically modified strains ΔstvP5 and ΔstvP4 which derived from Streptomyces spectabilis CCTCC M2017417, respectively. Their structures were elucidated via comprehensive spectroscopic analyses, including 1D and 2D NMR tests, and HR-ESI-MS data analysis. Notably, 1 and ansavaricin E represent the only two reported examples of heterocyclic ring-fused streptovaricins thus far, however, it only showed insignificant antibacterial activities against methicillin-resitant Staphylococcus aureus . PMID: 32492242 [PubMed - as supplied by publisher]
Source: Chemistry and Biodiversity - Category: Biochemistry Authors: Tags: Chem Biodivers Source Type: research