COVID-19 and cardiovascular injury: A role for oxidative stress and antioxidant treatment?

The coronavirus disease 2019 (COVID-19), seems to have a cardiovascular tropism characterized by high incidence of myocardial infarction especially for patients with severe infections recovered in intensive care units. In their letter, the Authors state that oxidative stress could play a pivotal role to determine cardiovascular complications in COVID-19. We agree about this issue. In particular, NADPH oxidase-2 (NOX-2), that it is considered one of the most important sources of superoxide anion in human [1], plays a role in systemic inflammation and pathogenesis of several RNA virus as the influenza virus [2].
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Letter to the editor Source Type: research