AR-12 Exhibits Direct and Host-targeted Antibacterial Activity toward Mycobacterium abscessus.
In conclusion, AR-12 is active against M. abscessus in vitro and in vivo, and does not antagonize the most frequently used anti-M. abscessus drugs. As such, AR-12 is a potential candidate to include in novel strategies to treat M. abscessus infections.
PMID: 32482678 [PubMed - as supplied by publisher]
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Zhang S, Zou Y, Guo Q, Chen J, Xu L, Wan X, Zhang Z, Li B, Chu H Tags: Antimicrob Agents Chemother Source Type: research