The DISC1 R264Q variant increases affinity for the dopamine D2 receptor and increases GSK3 activity

The Disrupted in schizophrenia 1 (DISC1) gene encodes a scaffolding protein that is involved in many neural functions such as neurogenesis, neural differentiation, embryonic neuron migration and neurotransmitter ...

Source: Molecular Brain - June 3, 2020 Category: Neuroscience Authors: Ping Su, Hailong Zhang, Albert H. C. Wong and Fang Liu Tags: Research Source Type: research