Impact of Saharan dust exposure on airway inflammation in patients with ischemic heart disease

Epidemiological studies found that increases in the concentrations of airborne particulate matter (PM) smaller than 10 microns diameter (PM10) in the ambient air due to desert dust outbreaks contribute to global burden of diseases, primarily as a result of increased risk of cardiovascular morbidity and mortality. No studies have investigated the possible association between desert dust inhalation and airway inflammation in patients with ischemic heart disease (IHD). Induced sputum was collected in 38 patients and analysed to determine markers of airway inflammation (Transforming Growth Factor- β1 [TGF-β1] and hydroxyproline) concentrations.
Source: Translational Research - Category: Research Authors: Source Type: research