Synthesis of a novel 89 Zr-labeled HER2 affibody and its application study in tumor PET imaging

ConclusionThe novel HER2 affibody for PET imaging was easily prepared with satisfactory labeling yield and radiochemical purity. [89Zr]Zr-DFO-MAL-Cys-MZHER2 is a potential candidate for detecting HER2 expression. It may play specific roles in clinical cancer theranostics.

Source: EJNMMI Research - June 2, 2020 Category: Radiology Source Type: research