Quantification and reliability of [ 11 C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung — a test-retest PET study in control subjects

ConclusionsThe kinetic behaviour and good repeatability of [11C]VC-002 as well as the novel lung image analysis methodology support its application in applied studies on drug-induced mAChR receptor occupancy and the pathophysiology of pulmonary disorders.Trial registrationClinicalTrials.gov identifier:NCT03097380, registered: 31 March 2017.
Source: EJNMMI Research - Category: Radiology Source Type: research