New-Onset Epilepsy in Women with First Time Seizures during Pregnancy

Publication date: Available online 2 June 2020Source: SeizureAuthor(s): Grace J. Ma, Sanya Yadav, Peter W. Kaplan, Emily Johnson
Source: Seizure - Category: Neurology Source Type: research

Related Links:

The vaginal mesh scandal betrayed the intimate trust that should exist between doctor and patient, whatever their sexWhatever comes next in the vaginal mesh scandal, let ’s hope that it spells the end of the “shut up and put up” medical culture when it comes to female healthcare.The Independent Medicines and Medical Devices Safety Review, led by Baroness Julia Cumberlege,spent two years looking into meshes. It also scrutinised Primodos hormonal pregnancy tests and theepilepsy treatmentsodium valproate– both thought to cause birth defects.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Vaginal mesh implants Society Health Epilepsy Sexual health Women NHS Life and style Medical research Science Source Type: news
Publication date: October 2020Source: Epilepsy &Behavior, Volume 111Author(s): Makiko Egawa, Keiko Hara, Masami Ikeda, Eri Kono, Susumu Miyashita, Naoyuki Miyasaka, Motoki Inaji, Taketoshi Maehara, Masayuki Yoshida
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
In this study, we aimed to assess the needs and understand knowledge levels regarding pregnancy-related issues among Japanese WWE. We contacted 400 board-certified epileptologists and asked them to administer our questionnaire to their patients; 51 responses were analyzed. Among all participating WWE, 100% were taking medication at the time of the study, 34% had given birth, and 63% expressed a desire to have children in the near future. Additionally, the median questionnaire score on pregnancy-related matters was as low as 9.5 out of 13 points. Only 31% of WWE knew that the mode of delivery is not always cesarean delivery...
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
CONCLUSION: Our study suggests that patients and carers do not wish to stop valproate or engage in PPP despite being made aware of MHRA guidance. PMID: 32568279 [PubMed - in process]
Source: Journal of the Royal College of Physicians of Edinburgh - Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research
(King's College London) A new study of childhood epilepsy has identified the world's first environmental risk factor for the disease - maternal smoking in pregnancy, and discovered a new genetic association with the condition, pointing to potential new treatments for the disease.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
Abstract We aimed to confirm or reject previous reports on the association of prenatal antibiotic exposure and development of epilepsy in offspring by accounting for known and unidentified confounding factors. In a retrospective cohort investigation, we enrolled children aged 3-18 years born between 1998 and 2012 at a single regional hospital and their mothers. A computerized medication database was linked with hospital records. The exposed group included children whose mothers purchased 1 or more antibiotic medications for use during pregnancy. Epilepsy was defined by epilepsy diagnosis and/or by chronic dispensi...
Source: The Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Authors: Tags: J Clin Pharmacol Source Type: research
This study was aimed at elucidating the heritable effects and programming mechanism of TLE in offspring rats induced by prenatal dexamethasone exposure (PDE). Pregnant Wistar rats were injected subcutaneously with dexamethasone (0.2 mg/kg day) from gestational day 9 to 20. The F1 and F2 generations of male offspring were administered lithium pilocarpine (LiPC) for electroencephalography and video monitoring in epilepsy or behavioral tests. Results showed that the PDE + LiPC group exhibited TLE susceptibility, which continued throughout F2 generation. Expression of hippocampal glucocorticoid rec...
Source: Archives of Toxicology - Category: Toxicology Authors: Tags: Arch Toxicol Source Type: research
The prevalence of epilepsy is between 4 and 10 per 1000 in the developed world, similar between men and women [1]; therefore, epilepsy is one of the most common chronic neurologic conditions affecting women of child-bearing age. While many women with epilepsy experience no change in seizure frequency during pregnancy, up to one-third of women have an increase in seizure frequency [2]. These increases are likely mediated by multiple factors including changes in ASD (anti-seizure drug) metabolism, changes in hormone levels, medication compliance, and sleep deprivation.
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research
CONCLUSION: In WWE, epilepsy classification, number of AEDs taken, and frequency of seizures are not significantly correlated with delivery and fetal condition. This data could be used as a clinical reference for physicians to provide useful information to WWE if they are concerned about their pregnancies. PMID: 32419394 [PubMed - in process]
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
Abstract Autism spectrum disorders (ASDs) and epilepsy are often comorbid. The basis for this co-occurrence remains unknown; however, inflammatory stressors during development are a shared risk factor. To explore this association, we tested the effect of repeated immunizations using a heat-killed preparation of the stress-protective immunoregulatory microbe Mycobacterium vaccae NCTC 11659 (M. vaccae) on the behavioral and epileptogenic consequences of the combined stress-terbutaline (ST) rat model of ASD-like behavior/epilepsy. Repeated immunization of the dam with M. vaccae during pregnancy, followed by immunizat...
Source: Brain, Behavior, and Immunity - Category: Neurology Authors: Tags: Brain Behav Immun Source Type: research
More News: Epilepsy | Neurology | Pregnancy | Women