Does type of immunosupression influence the course of Covid-19 infection?

Minotti Chiara and colleagues and Ya Goa and colleagues have evaluated the burden of immunosupression on Covid-19 outcomes.1,2 Coronavirus disease 19 (Covid-19) is a new challenge for physicians, especially for those who treat patients with immunocompromised status. Pathophysiology of Covid-19 is complex and a combination of factors is responsible for the hyperinflammatory state leading a cytokine release syndrome in some patients.3 Few studies have reported that different biological features such as the cytokine release,3 a defect in type I-interferon response4 and/or polymorphisms of renin-angiotensin aldosterone system may play a major role in the heterogenicity of the disease.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research