von Willebrand Factor and Factor VIII Clearance in Perioperative Hemophilia A Patients.

CONCLUSION:  VWF:Ag and VWF:GPIbM levels increase postoperatively, most significantly in patients with blood type non-O or medium risk surgery. Lower VWF antigen levels did not lead to clinically relevant higher FVIII clearance. VWF:Ag or VWF:GPIbM levels were not associated with perioperative hemorrhage.
PMID: 32480417 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - May 31, 2020 Category: Hematology Authors: van Moort I, Bukkems LH, Heijdra JM, Schutgens REG, Laros-van Gorkom BAP, Nieuwenhuizen L, van der Meer FJM, Fijnvandraat K, Ypma P, de Maat MPM, Leebeek FWG, Meijer K, Eikenboom J, Mathôt RAA, Cnossen MH, OPTI-CLOT Study Group Tags: Thromb Haemost Source Type: research