The way we approach Mental Health today is broken beyond repair. The question is, what comes next, and how fast can we get there?

The hidden links between mental disorders (Nature): In 2018, psychiatrist Oleguer Plana-Ripoll was wrestling with a puzzling fact about mental disorders. He knew that many individuals have multiple conditions — anxiety and depression, say, or schizophrenia and bipolar disorder. He wanted to know how common it was to have more than one diagnosis, so he got his hands on a database containing the medical details of around 5.9 million Danish citizens. He was taken aback by what he found. Every single mental disorder predisposed the patient to every other mental disorder — no matter how distinct the symptoms. “We knew that comorbidity was important, but we didn’t expect to find associations for all pairs,” says Plana-Ripoll, who is based at Aarhus University in Denmark. The study tackles a fundamental question that has bothered researchers for more than a century. What are the roots of mental illness? … The idea that mental illness can be classified into distinct, discrete categories such as ‘anxiety’ or ‘psychosis’ has been disproved to a large extent. Instead, disorders shade into each other, and there are no hard dividing lines — as Plana-Ripoll’s study so clearly demonstrated… As a result, the world’s largest funder of mental-health science, the US National Institute of Mental Health, changed the way it funded research. Beginning in 2011, it began demanding more studies of the biological bas...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Technology anxiety biological bipolar-disorder depression Genetics JAMA Psychiatry mental illness mental-disorders National-Institute-of-Mental-Health neuroanatomy psychopathology Resear Source Type: blogs

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A prospective study of a urine and plasma biomarker test for the prediction of gleason ≥3 + 4 prostate cancer in a mixed cohort. Scand J Urol. 2020 Jul 01;:1-5 Authors: Poulsen MH, Feddersen S, Albitar M, Poulsen CA, Lund M, Pedersen TB, Mortensen MA, Lund L Abstract Purpose: Definitive diagnosis of prostate cancer is based on biopsies, a procedure associated with side-effects. The use of biomarkers in blood and urine could potentially help clinicians select patients for whom biopsies are needed. The aim of the study was to test a new urine and plasma biomarker test in detecting medium...
Source: Scandinavian Journal of Urology - Category: Urology & Nephrology Tags: Scand J Urol Source Type: research
Patients hospitalised with COVID-19 who take statins are less likely to die than those who do not, a retrospective study published in Cell Metabolism suggests.
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
Authors: Santos CDSE, Filho LMDCL, Santos CAT, Neill JS, Vale HF, Kurnutala LN Abstract The 2020 pandemic caused by the novel coronavirus, COVID-19, had its headquarters in China. It causes Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and presents a broad spectrum of clinical manifestations, ranging from entirely asymptomatic through severe acute respiratory failure and death. Presuming a significant quantity of ventilator-dependent patients, several institutions strategically delayed elective surgeries. Particularly procedures performed involving the nasal mucosa, such as a transsphenoidal approach...
Source: Revista Brasileira de Anestesiologia - Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research
Authors: Sencan S, Edipoglu IS, Celenlioglu AE, Yolcu G, Gunduz OH Abstract Background: We aimed to compare interlaminar epidural steroid injections (ILESI) and bilateral transforaminal epidural steroid injections (TFESI) on pain intensity, functional status, depression, walking distance, and the neuropathic component in patients with lumbar central spinal stenosis (LCSS). Methods: The patients were divided into either the ILESI or the bilateral TFESI groups. Prime outcome measures include the numerical rating scale (NRS), Oswestry disability index (ODI), Beck depression inventory (BDI), and pain-free walking d...
Source: Korean Journal of Pain - Category: Anesthesiology Tags: Korean J Pain Source Type: research
Publication date: Available online 1 July 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Khaled Abdallah, Fadi Hamed, Nadeem Rahman, Shameen Salam, Jihad Mallat
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Arkansas reported its biggest single-day increase in coronavirus cases on Thursday, as the state's governor said concerns about the virus will be a valid excuse to vote absentee in the November election.
Source: Arkansas Business - Health Care - Category: American Health Source Type: news
Authors: Tünel M, Çakmak S, Tamam L, Demir T Abstract Normal pressure hydrocephalus (NPH), typically associated with the triad of gait disturbance, dementia and urinary incontinence, rarely presents with symptoms of mania, depression or psychosis and psychiatric disorders may complicate the diagnosis. Few cases of NPH and psychiatric disease comorbidity have been reported so far. In most of these cases, NPH was associated with depression and psychotic symptoms. Mania symptoms were also reported in a few cases those of which were associated with a history of bipolar disorder (BPD) or subthreshold BPD sym...
Source: Turk Psikiyatri Dergisi - Category: Psychiatry Tags: Turk Psikiyatri Derg Source Type: research
Authors: Şahan E, Parlakkaya Yıldız FB Abstract Hyponatremia can be asymptomatic or have a wide range of clinical presentations such as headaches, muscle cramps, nausea, seizures, coma, cerebral edema and may even result in death. Despite it has been suggested that duloxetine has a relatively less risk of hyponatraemia, the number of case reports are increasing. A 45- year old female patient with complaints of fear, anxiety, sleeplessness and headache was started on duloxetine (30 mg/day). In the first week of the treatment, she was admitted to the emergency service with dizziness, dry mouth, polyuria and polydi...
Source: Turk Psikiyatri Dergisi - Category: Psychiatry Tags: Turk Psikiyatri Derg Source Type: research
CONCLUSION: The Turkish Version of the BSDS, has been shown to be reliable and valid tool for screening bipolar disorder after removal of the item 4 of the original version of the scale. PMID: 32594489 [PubMed - in process]
Source: Turk Psikiyatri Dergisi - Category: Psychiatry Tags: Turk Psikiyatri Derg Source Type: research
CONCLUSION: In this study, it was determined that clozapine was effective as a mood stabilizer in Bipolar Affective Disorder treatment. The results show that clozapine reduces the episode frequency and the duration in rapid cycling Bipolar Affective Disorder which does not respond to all conventional treatments, including lithium, valproic acid, carbamazepine and antipsychotic drugs. PMID: 32594488 [PubMed - in process]
Source: Turk Psikiyatri Dergisi - Category: Psychiatry Tags: Turk Psikiyatri Derg Source Type: research
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