Predicting the Acute Liver Toxicity of Aflatoxin B1 in Rats and Humans by an In Vitro –In Silico Testing Strategy

ConclusionsQuantitative in vitro in vivo extrapolation (QIVIVE) using PBK modeling ‐based reverse dosimetry can predict AFB1 doses that cause acute liver toxicity in rats and human.

Source: Molecular Nutrition and Food Research - June 1, 2020 Category: Food Science Authors: Ixchel Gilbert ‐Sandoval, Sebastiaan Wesseling, Ivonne M. C. M. Rietjens Tags: Research Article Source Type: research