Hirschsprung disease and anorectal malformations — An uncommon association

The simultaneous occurrence of Hirschsprung disease (HD) and anorectal malformation (ARM) is extremely rare, with only a very limited amount of cases published in the literature.Constipation is a major problem in patients operated for ARM, and biopsies from the distal rectum in patients with ARM may not show ganglion cells owing to different reasons, leading to a false positive diagnosis of HD. A pull-through procedure for HD after previous anorectoplasty for ARM always leads to fecal incontinence.
Source: Journal of Pediatric Surgery - Category: Surgery Authors: Source Type: research

Related Links:

Conclusion: Tetrapanax papyriferus and hederagenin relieved sciatica by reducing inflammation levels, inhibiting p38 MAPK phosphorylation, and decreasing the levels of dorsal root ganglion proteins. PMID: 32617100 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
AbstractBackgroundPosterior tibial nerve stimulation (PTNS) is a minimally invasive approach with little adverse effects, but obtaining good results as shown in the different scales for the evaluation of the severity of incontinence. The aim of this study was to determine the effects of PTNS based on manometric determinations of the anal sphincter and severity during a period of treatment of 6  months (18 sessions).Patients and methodsA prospective interventional study of patients with fecal incontinence was performed. Subjects underwent one 30-min session every week for 12  weeks, followed by 6 sessions every 2&...
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
AbstractPurposeEvaluate the impact of fecal incontinence (FI) and chronic constipation (CC) on the quality of life (QoL) in a large population and determine if a threshold of symptom scores was associated with alterations to QoL.MethodsA total of 422 outpatients with FI (n = 186), CC (n = 186), and mixed FI-CC (n = 50) referred for anorectal manometry were included prospectively. All patients completed a set of questionnaires to evaluate the severity of FI and CC (respectively Jorge and Wexner and KESS scores) and their impact on QoL (Gastrointestinal Quality of Life Index (GIQLI)).Resul...
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
Discussions with Elders about Housing 
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Conclusion: BTX-A is an effective and well-tolerated treatment in patients with benign prostatic hyperplasia (BPH) who are candidates of TURP and simultaneously suffer from OAB symptoms. PMID: 32617023 [PubMed]
Source: Clinical Pharmacology: Advances and Applications - Category: Allergy & Immunology Tags: Clin Pharmacol Source Type: research
Authors: Tienza A, Graham PL, Robles JE, Diez-Caballero F, Rosell D, Pascual JI, Patel MI, Mungovan SF Abstract PURPOSE: Continence assessment is an essential component of follow-up after radical prostatectomy (RP). Several methods exist to assess the severity of urinary incontinence (UI). Our study examined the relationship and degree of agreement between International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) scores and the number of pads used in a 24-hour period in the assessment of UI following RP. METHODS: Continence was prospectively assessed in 746 men from a Spanish urology clinic ...
Source: International Neurourology Journal - Category: Urology & Nephrology Tags: Int Neurourol J Source Type: research
CONCLUSION: LUTS were highly prevalent in patients with BD, and the severity and current activity of BD were correlated with frequency, nocturia, urgency, and urinary incontinence. Therefore, a urological evaluation of patients with BD in whom the activity and severity of the disease is elevated should be carried out comprehensively and patients should be managed accordingly. PMID: 32615677 [PubMed]
Source: International Neurourology Journal - Category: Urology & Nephrology Tags: Int Neurourol J Source Type: research
This article aims to provide an overview of Hirschsprung's disease, outlining the aetiology of HSCR and management of children with HSCR.
Source: Surgery (Oxford) - Category: Surgery Source Type: research
ConclusionsIncluding the above-listed items in the patient history might facilitate differentiation of low back pain and sciatica due to STCs from that due to disc problems or degenerative or inflammatory disorders.
Source: Acta Neurochirurgica - Category: Neurosurgery Source Type: research
Publication date: Available online 11 November 2016 Source:Surgery (Oxford) Author(s): Sumita Chhabra, Simon E. Kenny Hirschsprung's disease (HSCR) is characterized by a lack of enteric nervous system ganglion cells (aganglionosis) in a variable extent of distal bowel. It is the most common congenital bowel motility disorder, and affected neonates usually present with distal intestinal obstruction in the first few days of life. Current treatment involves resection of the aganglionic bowel and a ‘pull-through’ procedure to bring the normally innervated bowel down to the anal margin. Despite advances in surgery,...
Source: Surgery (Oxford) - Category: Surgery Source Type: research
More News: Constipation | Ganglions | Incontinence | Pediatrics | Surgery