Antibodies to nodal/paranodal proteins in paediatric immune-mediated neuropathy

Patients with nodal/paranodal antibodies represent a specific subgroup of inflammatory peripheral neuropathies, whose clinical presentation with a prolonged subacute phase, additional symptoms such as ataxia and tremor, and poor treatment response to IV immunoglobulin (IVIG) often differs from classic Guillain-Barré syndrome (GBS) or chronic inflammatory demyelinating polyneuropathy (CIDP).1

Source: Neurology Neuroimmunology and Neuroinflammation - June 1, 2020 Category: Neurology Authors: De Simoni, D., Ricken, G., Winklehner, M., Koneczny, I., Karenfort, M., Hustedt, U., Seidel, U., Abdel-Mannan, O., Munot, P., Rinaldi, S., Steen, C., Freilinger, M., Breu, M., Seidl, R., Reindl, M., Wanschitz, J., Lleixa, C., Bernert, G., Wandinger, K.-P. Tags: Guillain-Barre syndrome, Chronic inflammatory demyelinating polyneuropathy Clinical/Scientific Notes Source Type: research