Formation of ultralong DH regions through genomic rearrangement
Cow antibodies are very unusual in having exceptionally long CDR H3 regions. The genetic basis for this length largely derives from long heavy chain diversity (DH) regions, with a single “ultralong” DH, IGHD8–...
Source: BMC Immunology - Category: Allergy & Immunology Authors: Brevin A. Smider and Vaughn V. Smider Tags: Research article Source Type: research
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