Impact of ABVD chemotherapy on ovarian reserve after fertility preservation in reproductive-aged women with Hodgkin lymphoma

ConclusionAlthough ABVD is considered to be of low gonadotoxic risk, the decrease in AMH was greater than expected for patients ’ age, and 15% of patients needed more aggressive therapy during follow-up. Type of FP was not associated with decline in ovarian reserve. Reproductive-aged women with HL should have the opportunity for FP counseling before starting treatment.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research