Emerging Roles of PET/MR in the Pediatric Hospital
Add “improving” before “detection”? PET/MR is beneficial particularly in pediatric patients who undergo recurrent imaging, such as those with cancer or chronic inflammatory disease. PET/MR has advantages compared with PET/computed tomography, including decreased radiation exposure and superior c haracterization of soft tissue. Ongoing challenges include reducing examination duration and costs and detection of pulmonary lesions. Accepted clinical applications of PET/MR in pediatric patients are evaluation of epileptic foci and diagnosis, staging, and follow-up of solid tumors. PET/MR also ma y have a role in diagnosis and management of infectious and inflammatory conditions relevant to the pediatric population, including osteomyelitis and Crohn disease.
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00361A, PaperZhixing Ge, Junhua Zhao, Haibo Yu, Wenguang Yang, Peilin Zhou, Zhenning Wang, Lianqing Liu Currently, the mechanisms underlying the peritoneal metastasis of gastric cancer cells and the function of mesothelial cells during this process are unclear, primarily due to the absence of an effective... The content of this RSS Feed (c) The Royal Society of Chemistry
Chem. Commun., 2020, Advance Article DOI: 10.1039/D0CC03614E, CommunicationWentao Zhang, Hyunjun Choi, Bo Yu, Dong-Hyun Kim Iron oxide nanocube patched Janus magnetic porous silica nanocarriers are synthesized and it is expected to be used for a new type of multifunctional carriers in image guided cancer therapeutic applications. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
NIEHS grantees study pet dogs to better understand how human exposure to everyday chemicals may lead to cancer and other conditions. (read more)
New findings from the Agricultural Health Study suggest exposure to certain pesticides may increase risk of renal cell carcinoma. (read more)
NIEHS and Canadian scientists discover that cancer cells with mutated BRCA1 and BRCA2 genes died when they lacked a protein called APE2. (read more)
Publication date: Available online 5 July 2020Source: Genes &DiseasesAuthor(s): Xi Liu, Jimin Xu, Jia Zhou, Qiang Shen
Have you guys ever had a patient in their 40s, rich family history of breast and ovarian cancer, tested positive for the mutation, but does not want any prophylactic surgery. How would you proceed with surveillance? Obviously routine mammography is needed. Would this be an indication for routine pelvic ultrasound (q 1 year)? I read somewhere that sometimes CA 125 is checked as well? (Though i thought tumor markers were more relevant in post diagnosis and prognostic situations)
AbstractObjectivesResults after trans-arterial radioembolisation (TARE) for intrahepatic cholangiocarcinoma (iCC) depend on the architecture of the tumour. This latter can be quantified through computed tomography (CT) texture analysis. The aims of the present study were to analyse relationships between CT textural features prior to TARE and objective response (OR), progression-free survival (PFS), and overall survival (OS).MethodsTexture analysis was retrospectively applied to 55 pre-TARE CT scans of iCCs, focusing attention on the histogram-based features and the grey-level co-occurrence matrix (GLCM). Texture features w...
AbstractObjectivesTo compare the previously defined six different histogram-based quantitative lung assessment (QLA) methods on high-resolution CT (HRCT) in patients with systemic sclerosis (SSc) –related interstitial lung disease (ILD).MethodsThe HRCT images of SSc patients with ILD were reviewed, and the visual ILD score (semiquantitative) and the severity of ILD (limited or extensive) were calculated. The QLA score of ILD was evaluated using the previously defined six different methods and parameters (different lung attenuation ranges, skewness, kurtosis, mean lung attenuation, and standard deviation [SD]). Pulmon...
ConclusionsT2W breast MRI with complete FOV of the axillary region has comparable diagnostic performance as T2W dedicated axillary MRI regarding assessment of node-negative and node-positive breast cancer. Optimization of T2W breast MRI protocol by including a complete FOV of the axillary region can, therefore, be recommended in clinical prac tice.Key Points• Breast MRI with complete field of view of the axillary region has comparable diagnostic performance as dedicated axillary MRI regarding assessment of node-negative and node-positive breast cancer.• Optimization of breast MRI protocol by including ...