The activation of NLRP3 inflammasome potentiates the immunomodulatory abilities of mesenchymal stem cells in a murine colitis model.

In conclusion, our findings suggest that the NLRP3 inflammasome components are expressed in hUCB-MSCs and its activation can regulate the differentiation capability and the immunomodulatory effects of hUCB-MSCs. PMID: 32475381 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32475381?dopt=Abstract

Source: BMB Reports - May 31, 2020 Category: Biochemistry Authors: Ahn JS, Seo Y, Oh SJ, Yang JW, Shin YY, Lee BC, Kang KS, Sung ES, Lee BJ, Mohammadpour H, Hur J, Shin TH, Kim HS Tags: BMB Rep Source Type: research

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