Safe Administration of Low Frequency rTMS in a Patient with Depression with Recurrent Antidepressant-Associated Hyponatremic Seizures

The incidence of antidepressant-associated hyponatremia ranges between 0.5 – 32% across various treatment settings, with elderly depressed individuals being at maximum risk(1). It is thought to happen via induction of syndrome of inappropriate antidiuretic hormone secretion (SIADH) and is characterized by nausea, myalgia, weakness and headache(2). Symptoms usually appear within two weeks of starting the offending agent, and are associated with serum sodium levels

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 31, 2020 Category: Neurology Authors: Milind Vijay Thanki, Sachin Pradeep Baliga, Soumya Parameshwaran, Naren P. Rao, Urvakhsh Meherwan Mehta, Jagadisha Thirthalli Source Type: research