Umbilical cord-derived mesenchymal stem cells in neurodegenerative disorders: from literature to clinical practice.

Umbilical cord-derived mesenchymal stem cells in neurodegenerative disorders: from literature to clinical practice.
Regen Med. 2020 Jun 01;:
Authors: Reyhani S, Abbaspanah B, Mousavi SH
Abstract
Mesenchymal stem cells (MSCs) have provided a promising tool for cell therapy. Umbilical cord (UC) is one of the best sources of MSCs since its collection is noninvasive, and effortless, and the cells from this source are more capable and prolific. It has been proven that the differentiation, migration and protective properties of UC-MSCs are superior compared with other kinds of stem cells. Moreover, incurable neurodegenerative diseases, such as Alzheimer's disease, multiple sclerosis, Parkinson's disease and Huntington, encourage scientists to apply UC-MSCs transplantation in order to find a definite treatment. This review will focus on the preclinical and clinical use of mesenchymal stem cells derived from human umbilical cord in the treatment of neurodegenerative disorders.
PMID: 32479211 [PubMed - as supplied by publisher]

Source: Regenerative Medicine - May 31, 2020 Category: Genetics & Stem Cells Authors: Reyhani S, Abbaspanah B, Mousavi SH Tags: Regen Med Source Type: research