Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial
Conclusions:
We confirmed the FAIM2-rs7138803 relationship with obesity and identified novel and consistent associations with heart rate in particular in type 2 diabetic subjects. Furthermore, our results suggest a possible association of this polymorphism with higher myocardial infarction risk in type-2 diabetic subjects, although this result needs to be replicated as it could represent a false positive.
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Dolores CorellaJose SorlíJosé GonzálezCarolina OrtegaMontserrat FitóMonica BullóMiguel Martínez-GonzálezEmilio RosFernando ArósJosé LapetraEnrique Gómez-GraciaLluís Serra-MajemValentina Ruiz-GutierrezMiquel FiolOscar ColtellErnest VinyolesXavie Source Type: research
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