MiADMSA ameliorate arsenic induced urinary bladder carcinogenesis in vivo and in vitro.

CONCLUSION: Early signs of urinary bladder carcinogenesis were observed in arsenic and DMA exposed rats which were linked to metal accumulation, oxidative/ nitrosative stress, 8-OHdG, MMP-9 and survivin which were reduced by MiADMSA possibly via its efficient chelation abilities in vivo and in vitro. PMID: 32474354 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32474354?dopt=Abstract

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 27, 2020 Category: Drugs & Pharmacology Authors: Sathua K, Srivastava S, Flora SJS Tags: Biomed Pharmacother Source Type: research