The Effect of Patient- and Treatment-Related Factors on Circuit Lifespan During Continuous Renal Replacement Therapy in Critically Ill Children
Objectives: To examine the effects of patient and treatment variables on circuit lifespan in critically ill children requiring continuous renal replacement therapy. Design: Retrospective observational study based on a prospective registry. Setting: Tertiary referral 30-bed PICU. Patients: One hundred sixty-one critically ill children undergoing continuous renal replacement therapy during an 8-year period (2007–2014) were included in the study. Interventions: Continuous renal replacement therapy. Measurements and Main Results: During the study period, 161 patients received a total of 22,190 hours of continuous renal replacement therapy, with a median duration of 74.75 hours (interquartile range, 32–169.5) per patient. Of the 572 filter circuits used, 276 (48.3%) were changed due to circuit clotting and 262 (45.8%) were electively changed. Median circuit life was 24.62 hours (interquartile range, 10.6–55.3) for all filters and significantly longer for those electively removed as compared to those prematurely removed because of clotting (35.50 hr [interquartile range, 16.9–67.6] vs 22.00 hr [interquartile range, 13.8–42.5]; p
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Publication date: Available online 11 July 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Yining Wang, Jianhua Zhou, Xuerui Li, Lina Ma, Xiaoan Cao, Wen Hu, Lu Zhao, Wenxian Jing, Xi Lan, Youquan Li, Xiaowei Gong, Qiwei Chen, Laszlo Stipkvits, Susan Szathmary, Kazimierz Tarasiuk, Zygmunt Pejsak, Yongsheng Liu
Publication date: Available online 11 July 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Claudine Fournier, Marta Aires de Sousa, Begoña Fuster Escriva, Leila Sale, Patrice Nordmann, Laurent Poirel
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