ABO blood group, glycosyltransferase activity and risk of venous thromboembolism

ABO blood group influence the risk of venous thromboembolism (VTE) by modifying A and B glycosyltransferases (AGT and BGT) activities that further modulates Factor VIII (FVIII) and von Willebrand Factor (VWF) plasma levels. The aim of this work was to evaluate the association of plasma GTs activities with VWF/FVIII plasma levels and VTE risk in a case-control study.

Source: Thrombosis Research - May 31, 2020 Category: Hematology Authors: Manal Ibrahim Kosta, Pascal Bailly, Monique Silvy, Noemie Saut, Pierre Suchon, Pierre-Emmanuel Morange, Jacques Chiaroni, David-Alexandre Tr égouët, Louisa Goumidi Tags: Full Length Article Source Type: research