MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1

Conclusions
MiR-29c acts as a tumour suppressor in GC by directly targeting ITGB1. Loss of miR-29c expression is an early event in the initiation of gastric carcinogenesis and may serve as a diagnostic and therapeutic biomarker for patients with GC.

Source: Gut - January 8, 2015 Category: Gastroenterology Authors: Han, T.-S., Hur, K., Xu, G., Choi, B., Okugawa, Y., Toiyama, Y., Oshima, H., Oshima, M., Lee, H.-J., Kim, V. N., Chang, A. N., Goel, A., Yang, H.-K. Tags: Pancreatic cancer Stomach Source Type: research