A clinical guide to the pathophysiology, diagnosis and treatment of osteosarcopenia

The importance of preserving musculoskeletal health into old age is marked by the adverse outcomes sarcopenia (loss of muscle mass and function) and osteoporosis (bone loss) may confer such as an increased risk of falls, fractures, frailty, disability and premature death [1]. The role of these metabolically active tissues also extends beyond maintaining mobility and independence. For instance, skeletal muscle insulin resistance has been identified as the largest defect in type II diabetes [2], and the loss of muscle mass and strength correlates with cardiovascular disease in older adults [3].

Source: Maturitas - May 31, 2020 Category: Primary Care Authors: Ben Kirk, Sarah Miller, Jesse Zanker, Gustavo Duque Source Type: research