Resveratrol suppresses gastric cancer cell proliferation and survival through inhibition PIM-1 kinase activity.

In conclusion, the proapototic and anti-proliferative effects of resveratrol in gastric cancer cells are likely to be mediated through suppression of PIM-1 kinase activity, which may represent a novel mechanism underlying its chemopreventive and anticarcinogenic actions.
PMID: 32473133 [PubMed - as supplied by publisher]

Source: Archives of Biochemistry and Biophysics - May 26, 2020 Category: Biochemistry Authors: Kim S, Kim W, Kim DH, Jang JH, Kim SJ, Park SA, Hahn H, Han BW, Na HK, Chun KS, Choi BY, Surh YJ Tags: Arch Biochem Biophys Source Type: research