Genetic and phenotypic frequency distribution of CYP2C9, CYP2C19 and CYP2D6 in over 3200 Han Chinese.

CONCLUSIONS: Polymorphisms and phenotypic changes of CYP2C9, CYP2C19 and CYP2D6 are relatively frequent in the Han Chinese population. Thus, preemptive pharmacogenetic testing of CYP2C9, CYP2C19 and CYP2D6 should be recommended prior to dosing substrate drugs.
PMID: 32469422 [PubMed - as supplied by publisher]

Source: Clinical and Experimental Pharmacology and Physiology - May 28, 2020 Category: Drugs & Pharmacology Authors: He L, Chen S, Li J, Xie X, Huang L, Kuang Y, Xu K, Huang W, Zhao Y, Yang G, Guo C Tags: Clin Exp Pharmacol Physiol Source Type: research