Saikosaponin D inhibits autophagosome ‑lysosome fusion and induces autophagy‑independent apoptosis in MDA‑MB‑231 breast cancer cells.

In conclusion, the findings of the present study suggest that SSD may induce apoptosis and block autophagic degradation, which provides further evidence of the association between the inhibition of autophagic degradation and cell death. PMID: 32468000 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32468000?dopt=Abstract

Source: Molecular Medicine Reports - May 31, 2020 Category: Molecular Biology Tags: Mol Med Rep Source Type: research