Penfluridol Triggers Mitochondrial-mediated Apoptosis and Suppresses Glycolysis in Colorectal Cancer Cells through Down-regulating Hexokinase-2.

CONCLUSION: Penfluridol triggers mitochondrial-mediated apoptosis and induces glycolysis inhibition via modulating HK-2 in CRC and provides a theoretical basis to support penfluridol as a repurposed drug for CRC patients. PMID: 32470200 [PubMed - as supplied by publisher]
Source: Anatomical Record - Category: Anatomy Authors: Tags: Anat Rec (Hoboken) Source Type: research