Challenges to Differente Hepatitis C Genotype 1 and 6: Results from a Field Study in Cambodia

ConclusionsHCV genotype 1b and genotype 6 non-a/non-b were most common. With Versant 2.0 (using 5 ′UTR and core information), genotype classification (1 or 6) remained inconclusive in 15% of samples. The locally available method (LightPower assay) failed to identify genotype 6 non-a/non-b, which highlights that methods using 5′UTR information only should not be used in Cambodia. Regional/nat ional guidelines should be explicit about this.Trial RegistrationThis study was performed as part of a larger cross-sectional study on the burden of hepatitis C coinfection in HIV patients in Cambodia (Clinical.trials.gov: HCV-Epi NCT02361541).
Source: Infectious Diseases and Therapy - Category: Infectious Diseases Source Type: research