Gender-specific Associations of CD36 Polymorphisms with the Lipid Profile and Susceptibility to Premature Multi-vessel Coronary Artery Heart Disease in the Northern Han Chinese.

CONCLUSIONS: Four common CD36 polymorphisms (rs1049673, rs7755, rs3211956, and rs3173798) were identified to be significantly associated with extreme lipid profiles and had statistically opposite gender-specific clinical lipid profile effects. Thus, the 3'-untranslated regions (3'-UTR) CD36 SNPs could be a novel target for metabolic abnormalities in males of the Han nationality from Northern China.
PMID: 32461018 [PubMed - as supplied by publisher]

Source: Gene - May 23, 2020 Category: Genetics & Stem Cells Authors: Du Y, Chen K, Liu E, Wang X, Li F, Liu T, Zheng X, Li G, Che J Tags: Gene Source Type: research