HLA-A gene variation modulates residual function of the pancreatic β-cells in children with type 1 diabetes.

CONCLUSIONS: HLA-A alleles are not associated with disease development nevertheless strongly influence a residual pancreatic β-cell function. The results suggest a different role of HLA class I and class II in type 1 diabetes pathogenesis. PMID: 32462851 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32462851?dopt=Abstract

Source: Pediatric Endocrinology, Diabetes, and Metabolism - May 27, 2020 Category: Endocrinology Authors: Hogendorf A, Abel M, Wyka K, Bodalski J, Młynarski W Tags: Pediatr Endocrinol Diabetes Metab Source Type: research