Should empiric therapies be used for male factor infertility?

Idiopathic male infertility is defined as abnormal semen parameters without an underlying cause. The primary treatment option used in this patient population is empiric medical therapy (EMT). Hormone treatment, particularly antiestrogens, is the most widely used method of EMT for idiopathic male infertility. Specifically, clomiphene citrate (CC), anastrozole, and human chorionic gonadotropin (hCG) are the most commonly prescribed (1). For idiopathic male infertility EMT is a moderately effective treatment option with regards to improvement in semen parameters and pregnancy rate, but no clear predictors have been identified to determine which patients will respond optimally.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Fertile battle Source Type: research