RefleXion to collaborate with Merck on clinical trial
Radiation therapy equipment developer RefleXion Medical has announced a clinical...Read more on AuntMinnie.comRelated Reading: RefleXion raises $100M in equity round RefleXion sells first X1 rad therapy machine RefleXion gets FDA nod for rad therapy RefleXion files 510(k), opens manufacturing facility RefleXion Medical secures $60M loan
CONCLUSIONS: Our initial results of active scanning PT for primary liver cancer demonstrated the feasibility, safety, and effectiveness of this advanced technique in this setting. The potential of the combination of PT with other locoregional therapies is under evaluation. PMID: 32648818 [PubMed - as supplied by publisher]
Publication date: September–October 2020Source: Reports of Practical Oncology &Radiotherapy, Volume 25, Issue 5Author(s): Fawzi Abuhijla, Samer Salah, Maysa Al-Hussaini, Issa Mohamed, Imad Jaradat, Abdulmajeed Dayyat, Hanan Almasri, Alaa Allozi, Ayah Arjan, Abdelatif Almousa, Ramiz Abu-Hijlih
Radiation therapy (RT) is part of definitive treatment for patients with unresectable non-small cell lung cancer (NSCLC). Despite major technological advances in imaging and conformal delivery techniques, the tolerances of adjacent normal tissues continue to limit target volume doses [1,2]. In patients receiving RT for thoracic malignancies, the most frequent toxicities occur in the lungs and/or heart. Radiation-induced cardiac toxicity (RICT) may present as multiple pathologies including myocardial fibrosis, ischemic heart disease, valvular abnormalities and pericarditis .
Multiple forms of definitive radiotherapy are acceptable alternatives to more prolonged radiotherapy regimens for men with intermediate-risk prostate cancer (PCa) and can be considered for men with low-risk disease who decline active surveillance. Stereotactic body radiotherapy (SBRT) is an external beam radiotherapy modality in which large radiation doses are delivered over five or fewer fractions. Two forms of brachytherapy -- permanent seed implant low dose rate brachytherapy (LDR-BT) and temporary interstitial implant high dose rate brachytherapy (HDR-BT) -- are also options.
Authors: Hussain T, Mattheis S, Lang S Abstract The incidence of human papillomavirus (HPV)-positive oropharyngeal carcinomas is increasing worldwide. Due to a markedly different response to treatment compared to HPV-negative oropharyngeal carcinomas, determining the ideal therapeutic approach can be challenging. Particularly in never-smokers, HPV-positive oropharyngeal carcinomas respond well to primary radiation therapy; at the same time recent studies indicate comparable survival after primary surgery. For stage I tumors according to TNM‑8, retrospective analyses show very good oncologic outcomes aft...
Conclusion: Awareness of rare sellar neuroblastomas will allow the accumulation of clinicopathologic information that may facilitate the understanding of their origin, clinical features, neuroimaging characteristics, and pertinent adjuvant treatment. PMID: 32637218 [PubMed]
Surface-guided radiation therapy (SGRT) employs a non-invasive real-time optical surface imaging (OSI) technique for patient surface motion monitoring during radiotherapy. The main purpose of this study is to ...
CONCLUSIONS: QOL is largely preserved in brain metastasis patients treated with SRS. Higher RPA class, upfront whole-brain radiation therapy, and greater intracranial disease burden are independent predictors of post-SRS QOL deterioration. Worse pre-SRS QOL predicts shorter survival. Assessment of QOL is recommended in brain metastasis patients managed with SRS. PMID: 32650308 [PubMed - as supplied by publisher]
Our study shows the distribution patterns and prognoses of distant metastases among 4 histological types in NPC. A nomogram was constructed for clinical use based on 4 independent prognostic risk indicators, including histology, radiation therapy, chemotherapy and metastatic status. Our findings provide a reference for clinical decision ‐making and future diagnostic screening tests for NPC with distant metastases. AbstractCurrently, the features and prognosis of nasopharyngeal carcinoma (NPC) with distant metastases are still rarely reported. Thus, the main purpose of our study was to investigate the metastasis patterns ...
We would like to thank Sandra Kos for her letter , giving us the opportunity to clarify some statements made in our review .