Novel Catheter Design Enables Transurethral Catheterization of Male Mice.

Novel Catheter Design Enables Transurethral Catheterization of Male Mice. Am J Physiol Renal Physiol. 2020 May 28;: Authors: Lamanna OK, Hsieh MH, Forster CS Abstract The male mouse is underrepresented in research of the urinary tract due to the difficulty of transurethral catheterization. As a result, there is a lack of analysis of gender differences in urinary tract research. Here, we present a novel catheter design and technique that enables urethral catheterization of male mice. Our catheterization technique uses the resistance met at the level of the external urinary sphincter and prostate to guide the retraction, positioning, and advancement of the catheter into the urinary bladder. We have shown that this method can be used to reproducibly catheterize 12 male mice with minimal urogenital trauma. This method will facilitate the expansion of research into sex differences in various genitourinary conditions that require transurethral catheterization of mice. PMID: 32463724 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Renal Physiology - Category: Physiology Authors: Tags: Am J Physiol Renal Physiol Source Type: research