Parotid follicular lymphoid hyperplasia - a rare entity: the challenges in differential diagnosis

ABSTRACT A 61-year-old female patient presented a nodular lesion located in the right buccal mucosa with a 3-month evolution. Clinical hypotheses of salivary duct cyst and mucocele were proposed, and the patient underwent excisional biopsy. Microscopically, a well-circumscribed and encapsulated lymphoid aggregate fragment was observed, characterized by layers of well-differentiated small lymphocytes and collections of reactive lymphoblasts. These findings, associated with immunohistochemistry, established the diagnosis of follicular lymphoid hyperplasia. Currently, the patient is well, under follow-up after six months.RESUMEN Paciente del sexo femenino de 61 a ños de edad exhibió lesión nodular localizada en mucosa yugal derecha con tiempo de evolución de tres meses. Se establecieron las hipótesis clínicas de quiste del ducto salival y mucocele, y la paciente se sometió a una biopsia excisional. Microscópicamente, se observó un fragmento de agreg ado linfoide bien circunscrito y encapsulado, caracterizado por capas de linfocitos pequeños bien diferenciados y colecciones de linfoblastos reactivos. Esos hallazgos, asociados al estudio inmunohistoquímico, basaron el diagnóstico de hiperplasia folicular linfoide. Al presente, la paciente se e ncuentra bien, bajo seguimiento seis meses después.RESUMO Paciente do sexo feminino, 61 anos de idade, exibiu les ão nodular localizada em mucosa jugal direita com evolução há três meses. As hipóteses clínicas de cisto do...

Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - May 29, 2020 Category: Pathology Source Type: research