A novel risk factor for predicting anti-tuberculosis drug resistance in patients with tuberculosis complicated with type 2 diabetes mellitus

The world strives for progress towards accelerating the decline rate of tuberculosis (TB) incidence from 2% to 10% per year to reach the 2035 milestone of the End TB Strategy (WHO 2014). However, the appearance and growing incidence of drug-resistant TB impedes this progress largely. WHO estimated that in 2018, there were 484000 new cases with resistance to rifampicin (the most effective first-line drug) and 78% of these cases were multidrug-resistant TB (MDR-TB) (WHO 2019). Early and accurate diagnosis is of utmost importance to mitigate burden brought by MDR-TB (WHO 2010).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research

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Bayer's finerenone meets primary endpoint in Phase III FIDELIO-DKD renal outcomes study in patients with chronic kidney disease and type 2 diabetesFinerenone significantly reduced the combined primary endpoint of chronic kidney disease progression, kidney failure or kidney death versus placebo when added to standard of care / Finerenone significantly reduced the combined key secondary endpoint of cardiovascular death or non-fatal cardiovascular events / Chronic kidney disease impacts 4 in 10 patients with type 2 diabetes and is a deadly condition that is underrecognized / Finerenone is the first investigational non-steroid...
Source: Bayer IR Newsfeed: Events - Category: Pharmaceuticals Source Type: news
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