Reversal of anti-drug antibodies against tumor necrosis factor inhibitors with addition of immunomodulators: A systematic review and meta-analysis

ConclusionIn our meta-analysis, addition of immunomodulators to TNF- α inhibitors was shown to restore the clinical response in 74% of the patients by either decreasing or completely eliminating anti-drug antibody levels. Further long-term multicenter studies are needed to validate these findings.
Source: Indian Journal of Gastroenterology - Category: Gastroenterology Source Type: research