Target-based genomic profiling of ctDNA from Chinese non-small cell lung cancer patients: a result of real-world data

ConclusionIn Chinese NSCLC patients,EGFR mutation was significantly associated with female, younger age (<  65 years), and adenocarcinoma. Genomic profiles of NSCLC were associated with the treatment history;TP53 mutation was significantly more frequent in the patients with history of radiochemotherapy/chemotherapy therapy. Various multiple genes co-mutation panels, especially EGFR and KRAS co-mutation, were observed in the ctDNA of Chinese NSCLC patients.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research