Low-frequency transcranial magnetic stimulation of the left dorsal premotor cortex in patients with cervical dystonia

Botulinum toxin has been considered as the treatment of choice for patients with cervical dystonia (CD) [1]. Although its effect is usually helpful, botulinum toxin can cause serious complications [1]. Thus, development of a new treatment strategy for patients with CD is required to overcome the limitations of the current treatment. Based on pathophysiology of dystonia including loss of inhibition and aberrant plasticity within the brain [2], non-invasive brain stimulation (NIBS) techniques such as repetitive transcranial magnetic stimulation (rTMS) have been applied to patients with CD to normalize disrupted function in certain brain regions and improve their symptoms [3].

Source: Parkinsonism and Related Disorders - May 26, 2020 Category: Neurology Authors: Hae-Won Shin, Mark Hallett Tags: Correspondence Source Type: research