Bioactive Properties of Syzygium cumini (L.) Skeels Pulp and Seed Phenolic Extracts

This study aimed to determine the centesimal composition and physicochemical characteristics of the pulp and seed of S. cumini (L.) Skeels, as well as the content of total phenolic compounds and the antioxidant, antibacterial, antibiofilm and anti-quorum sensing (QS) activities of the phenolic extracts obtained from the pulp and the seeds of this fruit. The in vitro antibacterial and anti-QS activities of active films incorporating phenolic extracts were also evaluated. Additionally, we performed molecular docking of phenolic compounds present in jambolan with the CviR QS regulator of Chromobacterium violaceum. The composition and physicochemical characteristics of the samples presented similar values to those found for the species. However, the seed phenolic extract had a higher content of phenolic compounds and antioxidant activity than the pulp. Both phenolic extracts presented antibacterial activity against Aeromonas hydrophila, C. violaceum, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica serovar Typhimurium, Serratia marcescens, Listeria monocytogenes, and Staphylococcus aureus. The seed phenolic extract was particularly inhibitory against S. aureus. The pulp phenolic extract inhibited swarming motility and biofilm formation of A. hydrophila, E. coli, and S. marcescens in sub-MIC concentrations. The pulp and seed phenolic extracts inhibited violacein production in C. violaceum. Films incorporating both phenolic extracts inhibited the growth of bacteria, pa...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research

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AbstractThe aims of this work were to identify in vivo manifestations of antioxidant activity ofLactobacillus strains isolated from healthy human biotopes and to show the possibility of protective action of the selected strain on the model of oxidative stress induced by paraquat in the model of early Parkinson ’s disease (PD) in mice. We studied the protective effects of 14Lactobacillus strains belonging to five species on the lifespan of the soil nematodeCaenorhabditis elegans experiencing oxidative stress induced by paraquat. TheLactobacillus strains used in this study were selected previously based on their abilit...
Source: World Journal of Microbiology and Biotechnology - Category: Microbiology Source Type: research
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Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
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Source: NYT - Category: American Health Authors: Tags: Agriculture and Farming Migrant Labor (Agriculture) Shortages States (US) Fruit Coronavirus (2019-nCoV) Blueberries Food Agriculture Department New Jersey Workplace Hazards and Violations Source Type: news
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Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research
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Source: Innovative Food Science and Emerging Technologies - Category: Food Science Source Type: research
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Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
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Source: LWT Food Science and Technology - Category: Food Science Source Type: research
Authors: Bozov P, Girova T, Prisadova N, Hristova Y, Gochev V Abstract Antimicrobial activity of nineteen neo-clerodane diterpenoids, isolated from the acetone extracts of the aerial parts of Scutellaria and Salvia species (Lamiaceae) were tested against thirteen strains belonging to nine different species of pathogenic and food spoilage bacteria Aeromonas hydrophila, Bacillus cereus, Escherichia coli, Listeria monocytogenes, Proteus vulgaris, Pseudomonas aeruginosa, Pseudomonas fluorescens, Salmonella abony and Staphylococcus aureus as well as against two yeast strains belonging to species Candida albicans. Seven ...
Source: Natural Product Communications - Category: Biochemistry Tags: Nat Prod Commun Source Type: research
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Source: Orvosi Hetilap - Category: Journals (General) Authors: Tags: Orv Hetil Source Type: research
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