Feasibility and Accuracy of Transduodenal Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Solid Lesions Using a 19-Gauge Flexible Needle: A Multicenter Study.
Conclusions: The transduodenal approach for obtaining samples from solid lesions using a 19-G flexible needle seems feasible and accurate. PMID: 32447874 [PubMed - as supplied by publisher]
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) primarily provides cytologic samples. EUS-guided fine-needle biopsy (EUS-FNB) with needles that provide histologic specimens may enhance diagnostic yield and facilitate accessory tissue staining. Several different needle designs are currently available and design superiority is unknown. We designed a randomized controlled trial (RCT) comparing 2 commonly used EUS-FNB needles in their ability to provide histologic tissue samples (primary endpoint) and to reach an accurate diagnosis (secondary endpoint).
Conclusions Although they were not available for a significant number of patients, grading and Ki-67 values from cytology correlated with histology moderately to strongly. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Abstract | Full text
Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is recognized as an effective and safe means of obtaining tissue to diagnosis pancreatic cancer. Previous studies have shown no mortality difference in patients undergoing EUS-FNA despite the initial concern that its use would lead to increased tumor dissemination. However, studies have not assessed if this held true when compared to percutaneous aspiration, as both methods could lead to tumor seeding along the needle track. We aimed to investigate if EUS-FNA conferred any mortality benefit compared to percutaneous aspiration.
This study aims to evaluate what impact the number of years an attending physician has been performing EUSs has on EUS-FNA procedure time, FNA needle passes and complication rates.
Endoscopic Ultrasound (EUS) guided biopsy (FNA) is an accurate method for diagnosis of pancreato-biliary tumors (S>85%). However, the presence of a biliary stent has been reported to decrease diagnostic yield up to 47%, when staging for these tumors by EUS is performed, it ’s thought that this is because of the acoustic interference effect of the stent. The information about if a biliary stent (BS) could affect diagnostic yield when FNA is performed in patients with biliary stenosis protocol, is not fully answered.
Needle-based confocal laser endomicroscopy (nCLE) allows for real-time optical biopsies during endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). Little is known about the nCLE imaging of gastrointestinal subepithelial lesions (GI-SELs); therefore, we determined its feasibility.
Pancreatic cystic lesions (PCL) are increasingly identified on cross-sectional imaging. Types include intraductal papillary mucinous neoplasms (IPMN), mucinous cystic neoplasms (MCN), serous cystadenoma (SCA), solid pseudopapillary tumors (SPT) and pseudocysts. Given the risk of malignancy associated with MCN and IPMN with high risk features, accurate PCL diagnosis is essential. Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) of cyst fluid for cytology remains important for the classification of PCL, but is limited by the ability to obtain a sufficient sample and cellularity of fluid.
Endoscopic ultrasound (EUS) guided sampling with fine needle aspiration (FNA) or fine needle biopsy (FNB) is the standard of care for diagnosis of solid pancreatic lesions. Over last decade, a large number of gastroenterologists have received dedicated training in EUS as well as ERCP. For ERCP, overall low volume is associated with more adverse events and negative patient outcomes. However, data regarding volume of endosonographer and overall clinical outcomes for patient is not available. Aim of this study was to examine impact of volume of endosonographer on overall adequacy and diagnostic accuracy of EUS guided FNA of p...
Endoscopic ultrasound (EUS) has proved to be superior for the detection of pancreatic tumours and nodal metastases and other gastrointestinal malignancies. Several studies have described the role of EUS guided FNAC and confirmed the better accuracy of the technique. Here we present the increase in diagnostic yield with experience.
Endoscopic ultrasound fine needle aspiration (EUS-FNA) is a widely accepted method for sampling pancreatic cystic lesions (PCLs). Limitations to fluid aspiration can be due to sub-optimal needle gauge or difficulty accessing the PCL and thus can restrict the ability to provide sufficient fluid for analysis. We assessed PCL aspiration performance and diagnostic accuracy in a 19G flexible needle against standard FNA needles.