Eligibility criteria related to hormone therapy in acne clinical trials: A systematic review.

Hormones play a complex role in acne pathogenesis and treatment. Androgens typically increase the size and secretion of sebaceous glands, worsening acne, while estrogen counters androgen effect by direct local opposition, inhibition of androgen production, and gene regulation (Barros& Thiboutot, 2017; Beinenfeld et al, 2019). Despite multiple guidelines on acne management, there is a paucity of high-quality data on the treatment of acne among patients receiving hormone therapy (Beinenfeld et al, 2019; Del Rosso et al, 2015; Zaenglein et al, 2016).
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Letters to the Editor Source Type: research