[Incidental finding of leukocyte cell-derived chemotaxin 2  - Associated amyloidosis in a liver].

We report the case of a Syrian patient who benefited from a partial hepatectomy for the treatment of multiple metastasis of a colorectal adenocarcinoma. Microscopic analysis of the surgical specimen revealed numerous amyloid deposits that did not match any of the usual forms of liver amyloidosis after immunohistochemistry typing. Some morphologic features of the deposits were highly suggestive of ALECT2. Complementary immunohistochemical study and mass spectrometry confirmed the diagnosis.
PMID: 32446730 [PubMed - as supplied by publisher]

Source: Annales de Pathologie - May 19, 2020 Category: Pathology Authors: Gibier JB, Gilbertson JA, Perbet R, Leriche W, Truant S, Leteurtre E, Gillmore JD, Gnemmi V Tags: Ann Pathol Source Type: research