IJERPH, Vol. 17, Pages 3742: Initial Therapy, Regimen Change, and Persistence in a Spanish Cohort of Newly Treated Type 2 Diabetes Patients: A Retrospective, Observational Study Using Real-World Data
IJERPH, Vol. 17, Pages 3742: Initial Therapy, Regimen Change, and Persistence in a Spanish Cohort of Newly Treated Type 2 Diabetes Patients: A Retrospective, Observational Study Using Real-World Data International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17103742 Authors: Aida Moreno-Juste Beatriz Poblador-Plou Mercedes Aza-Pascual-Salcedo Francisca González-Rubio Sara Malo Julián Librero López Victoria Pico-Soler Eva Giménez Labrador Sara Mucherino Valentina Orlando Enrica Menditto Alexandra Prados-Torres Antonio Gimeno-Miguel The World Health Organization considers the non-adherence to medication a significant issue with global impact, especially in chronic conditions such as type 2 diabetes. We aim to study antidiabetic treatment initiation, add-on, treatment switching, and medication persistence. We conducted an observational study on 4247 individuals initiating antidiabetic treatment between 2013 and 2014 in the EpiChron Cohort (Spain). We used Cox regression models to estimate the likelihood of non-persistence after a one-year follow-up, expressed as hazard ratios (HRs). Metformin was the most frequently used first-line antidiabetic (80% of cases); combination treatment was the second most common treatment in adults aged 40–79 years, while dipeptidyl peptidase-4 inhibitors were the second most common in individuals in their 80s and over, and in patients with renal disease...
Lactation boosts the quantity and quality of insulin-producing beta cells in the pancreas, likely reducing a woman ’s risk of developing type 2 diabetes.
Breastfeeding reduces type 2 diabetes risk by boosting beta cells.
CONCLUSIONS: Low serum magnesium levels have a greater association with an increased risk of mortality compared to high levels. The type of dialysis fluid affects the magnesium concentration and the risk of death. PMID: 32651086 [PubMed - as supplied by publisher]
ConclusionThe predictions generated by the risk equations used in the COM showed good concordance both with the studies used to develop the model and with studies not included in the model. In particular, the concordance observed in the external dependent validation suggests that the COM accurately predicts obesity-related event rates observed in the studies used to develop the model. However, the impact of existing CV risk, as well as mortality, is a key area for future refinement of the COM. Our results should increase confidence in the estimates derived from the COM and reduce uncertainty associated with analyses using this model.
In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Exercise Slows Inappropriate Growth of Blood Vessels in a Mouse Model of Macular Degeneration https://www.fightaging.org/archives/2020/07/exercise-slows-inappropriate-growth-of-blood-vessels-in-a-mouse-model-of-macular-degeneration/ Excessive growth of blood vessels beneath the retina is a proximate cause of blindness in conditions such as macular degeneration. Researchers here provide evidence for physical activity to be influential in the pace at which this process of tissue...
According to the CDC, people with chronic diseases, such as obesity, hypertension and type-2 diabetes, are a staggering 12 times more likely to die from the coronavirus – and Black Americans have a higher prevalence of many of these conditions. In Baltimore, medical staff from Johns Hopkins are joining forces with "trusted messengers" – including faith leaders from a historic local mosque – to improve health outcomes for the Black community. Allison Aubrey, o f National Public Radio, reports.
TYPE 2 DIABETES is akin to walking a tightrope - one misstep and your blood sugar is out of balance. Which 50p vegetable has been proven to reduce blood sugar and prevent complications?
Barney Calman, pictured with former Olympic triple jumper Michelle Robinson ahead of testing the theory that carbohydrate in food broken down into single sugar molecules have the same impact on blood sugar levels.
DIABETES type 2 symptoms include unexplained weight loss, tiredness, and passing more urine than normal. But you could also be at risk of high blood sugar if you develop this unusual patch on your skin. Should you consider speaking to a doctor about diabetes symptoms?
This article provides practical guidance on the use of oral semaglutide in the primary care setting, based on evidence from clinical studies, including the phase 3a PIONEER program, and the authors' clinical experience. PMID: 32643514 [PubMed - as supplied by publisher]