The effects of shift work and sleep duration on cancer incidence in Alberta`s Tomorrow Project cohort

Publication date: August 2020Source: Cancer Epidemiology, Volume 67Author(s): Jessica McNeil, Emily Heer, Romy F. Willemsen, Christine M. Friedenreich, Darren R. Brenner
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research

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Conclusions: Benefits and risks for both the patient and the offspring especially in the long term regarding marijuana use should be carefully weighed for each specific case. Standardized dosing and duration of treatment need to be determined. Recommendations should be made by physicians with expert training and after careful patient evaluation for fully informed patients, whose preference should be respected. Legislations should encourage more active basic, translational, and clinical studies. PMID: 32627638 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
HOW to lose visceral fat: Belly fat raises the risk of some deadly diseases, including cancers, diabetes, and heart disease. But, making sure you get enough sleep could help to get rid of visceral fat. This is the perfect number of hours you should be resting for.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Does religion help or harm people with severe mental illness? In today’s Not Crazy podcast, Gabe and Lisa welcome Rachel Star Wither, host of the Inside Schizophrenia podcast, to discuss religion’s role (or lack thereof) in treating those struggling with schizophrenia or bipolar disorder. Rachel relates her personal experiences of mixing religion with her illness and shares how she currently manages to believe in God while keeping her faith “separate” from her symptoms. Tune in for a deep discussion on religion and severe mental illness, including Rachel’s 3-day exorcism experience at age 17....
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Disorders General Interview Not Crazy Podcast Schizophrenia Spirituality Source Type: blogs
Spending less time in REM sleep is linked to a greater overall risk of death from any cause as well as from cardiovascular disease and other diseases except for cancer, a new study finds.
Source: - Health - Category: Consumer Health News Source Type: news
This article describes cognitive behavioral therapy (CBT) for women with problematic menopausal symptoms, and provides the evidence from clinical trials of women going through the menopause, women with breast cancer treatment-induced symptoms and women with problematic symptoms in a work context. The CBT focus is primarily on vasomotor symptoms (VMS) but it also targets stress, low mood and sleep problems. CBT is a brief therapy (four to six sessions) that is theory- and evidence-based; it is acceptable to women and effectively reduces the impact of VMS, improves sleep and has benefits to quality of life. VMS frequency is ...
Source: Climacteric - Category: Geriatrics Authors: Tags: Climacteric Source Type: research
Authors: Zhan LH, Dong YJ, Yang K, Lei SS, Li B, Teng X, Zhou C, Luo R, Yu QX, Jin HY, Lv GY, Chen SH Abstract Suanzaoren decoction (SZRT), a classic Chinese herbal prescription, has been used as a treatment for insomnia for more than a thousand years. However, recent studies have found no significant effects of SZRT as a treatment for insomnia caused by gastric discomfort. Herein, we studied the effects of modified Suanzaoren decoction (MSZRD) on gastrointestinal disorder-related insomnia. The main constituents of MSZRD were spinosin (2.21 mg/g) and 6-feruloylspinosin (0.78 mg/g). A pentobarbital-ind...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
REV-ERBα (NR1D1) is a circadian clock component that functions as a transcriptional repressor. Due to its role in direct modulation of metabolic genes, REV-ERBα is regarded as an integrator of cell metabolism with circadian clock. Accordingly, REV-ERBα is first proposed as a drug target for treating sleep disorders and metabolic syndromes (e.g., dyslipidaemia, hyperglycaemia and obesity). Recent years of studies uncover a rather broad role of REV-ERBα in pathological conditions including local inflammatory diseases, heart failure and cancers. Moreover, REV-ERBα is involved in regulation of cir...
Source: Theranostics - Category: Molecular Biology Authors: Tags: Review Source Type: research
study group Abstract BACKGROUND: Previous studies have yielded inconsistent findings regarding the association between obstructive sleep apnea (OSA) and cancer in humans. RESEARCH QUESTION: Is there an association between indices of sleep-disordered breathing severity and cancer incidence in patients investigated for suspected OSA? STUDY DESIGN AND METHODS: Data from a large multicenter cohort of cancer-free patients investigated for OSA were linked to health administrative data to identify new-onset cancer. Kaplan-Meier survival analysis and Cox proportional-hazards models were used to evaluate the asso...
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research
Conclusions: Education level, sleep quality, smoking, the frequencies of use of several foods and seasonings, the preference for specific tastes, and various eating and living habits were associated with GaC. The findings offer important hints for further prospective investigations and for easy effective GaC-preventative strategy-making.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
Conclusion: Alteration of signal transduction by a drug is the goal of chemogenomics, a new branch formed by combination of chemistry and genomics. The proliferation, angiogenesis and apoptosis of cancer cells are regulated by cellular signaling of transcription factors, protein kinases, transmembrane receptors, extracellular ligands and some external factors like oncogenic mutations, ubiquitin-proteasome pathway with epigenetic changes. Traditional anticancer drugs either alter DNA synthesis or control cell division while new drugs retard tumor growth or induce apoptosis. The deterioration of dopaminergic neurons in subst...
Source: Current Signal Transduction Therapy - Category: Molecular Biology Source Type: research
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