MiR-210 in exosomes derived from CAFs promotes non-small cell lung cancer migration and invasion through PTEN/PI3K/AKT pathway.

CONCLUSION: MiR-210 secreted by CAFs-exo could promote EMT by targeting UPF1 and activating PTEN/PI3K/AKT pathway, thereby promoting NSCLC migration and invasion.
PMID: 32446904 [PubMed - as supplied by publisher]

Source: Cellular Signalling - May 20, 2020 Category: Cytology Authors: Yang F, Yan Y, Yang Z, Hong X, Wang M, Yang Y, Ye L, Liu B Tags: Cell Signal Source Type: research