Plasma metabolomic profiles associated with infant food allergy with further consideration of other early life factors

Metabolomic signatures may be helpful to identify biomarkers for food allergy that are both specific and robust [1, 2]. In children, liquid chromatography mass spectrometry analysis revealed increased levels of uric acid in serum of children with peanut allergy [3] and elevated lactate, creatinine and glutamine levels and lower lipid and nicotinic acid levels have been observed in young adults with peanut allergy [4]. Nuclear magnetic resonance (NMR) metabolomics allows simultaneous quantification of a large number of metabolites that are involved in different pathways [5, 6].
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - Category: Biomedical Science Authors: Source Type: research